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br Conclusions ERK and its phosphorylation
2019-07-02

Conclusions ERK 1/2 and its phosphorylation plays an essential role in the hippocampus and can be triggered by both ROS accumulation and excessive Ca2+. DBP exposure can also affect the production of ROS and Ca2+ in the hippocampus. The question therefore arises as to whether the cell injury or a
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ATP binding cassette transporters such as
2019-07-02

ATP-binding cassette transporters such as ABCA1 and ABCG1 are expressed on cell membranes to transport cholesterol from Bufalin molecular to HDL. These transporters help to improve RCT and reduce atherosclerosis. ABCA1 and ABCG1 gene expression are primarily induced by the stimulation of liver X re
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Considering these reports and with the aim of further
2019-07-02

Considering these reports, and with the aim of further investigating the mechanism by which the cAMP-Epac/PKA pathway activates eNOS, we have performed imaging experiments evaluating the effect of drugs that increase cAMP or modify its signalling pathways (PKA or Epac activators and inhibitors) on b
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Introduction Human cytomegalovirus CMV is
2019-07-01

Introduction Human cytomegalovirus (CMV) is a herpesvirus which has a ubiquitous and worldwide distribution, and is the most frequent cause of congenital infection (Kenneson and Cannon, 2007). The prevalence is around 0.5–1% of all live births and is the leading cause of sensorineural hearing loss
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Most infants in NICUs are
2019-07-01

Most infants in NICUs are hospitalized continuously from birth, and MRSA infections are largely considered to be horizontally transmitted. Various studies had reported that viable MRSA can be found on the hands of up to 17% of healthcare workers, and on 59% of the environmental surfaces in rooms of
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Arita et al reported that the mechanism
2019-07-01

Arita et al. reported that the mechanism of ST-segment elevation in inferior leads is right coronary artery hypoperfusion due to vasodilation by Bezold–Jarisch-like reflexes that are induced by stimulation of the orthopox in the intra-atrial septum during transseptal puncture and extension [3]. Som
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Development of an atrial esophageal fistula
2019-07-01

Development of an atrial–esophageal fistula is one of the most dreaded complications of AF ablation [78]. A relatively large-scale nonrandomized study revealed that the anatomical risk factor of a small LA-to-esophageal distance was the most important factor in esophageal ulceration when using an ir
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According to several cases earlier reported by Gandhi et al
2019-07-01

According to several cases earlier reported by Gandhi et al, the median time of acute pancreatitis occurring is 12 days (range: 9–16 days), from the last administration of BV, and most events occurred in the first course of BV treatment. One patient experienced recurrent pancreatitis in the fifth co
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We moreover confirmed previous evidence of
2019-07-01

We, moreover, confirmed previous evidence of a net increase of CT density of bone metastases after ZA treatment and demonstrated that the changes persist at a 24 months follow-up. This study and previous reports [24–26] have demonstrated significant sclerotic changes of BMs, more evident in patients
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br OPG RANK and RANKL
2019-07-01

OPG, RANK and RANKL contribute to the vicious cycle established between tumour methysergide and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several a
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br Materials and methods br Results br Discussion To
2019-07-01

Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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br Alternans and arrhythmogenesis in different clinical
2019-07-01

Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a
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AC regimens have also demonstrated better preventive effects
2019-07-01

AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst
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Schisandrol B what Thomas Hoeksema por su parte
2019-07-01

Thomas Hoeksema, por su parte, explica la paradoja del título del siguiente modo: “la destrucción (fuego) está moderada por la estabilidad y la armonía (reposo). La relación entre estas dos fuerzas es multidimensional y dialéctica”. Para Hoeksema, el segundo volumen poético de Pacheco se debe entend
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There is a lot to celebrate and applaud in this
2019-07-01

There is a lot to celebrate and applaud in this month\'s issue of , but also some sobering findings and a clear demonstration of the need for more research. To start with the positive, Osman Sankoh and fellow INDEPTH Network colleagues announce a new freely accessible repository of Health and Demogr
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