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Before the start of the study we
2019-04-20
Before the start of the study, we expected referral of up to 3% visceral leishmaniasis cases to the tertiary hospital for management of eventual complications. However, no referral was necessary because all adverse events were mild. Incidence of adverse events was about 47% during treatment and 63%
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In MM the optimal sequence or combination of
2019-04-20
In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first
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In Alexandre de Figueiredo and colleagues take a
2019-04-20
In , Alexandre de Figueiredo and colleagues take a step in this direction with their time-series analysis of trends in vaccine coverage and a suite of socioeconomic and demographic factors across 190 countries over 30 years. The main aim was to gauge where and when salvinorin coverage might fall bel
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To determine the discriminatory power of the ischiopubic
2019-04-20
To determine the discriminatory power of the ischiopubic index, the ROC curve was used (Fig. 3). The area under the curve for sex differentiation was 83.5% for the ischiopubic index. In the study N-(p-amylcinnamoyl) with a differentiation point of 100.47°, sensitivity of 82%, specificity of 78%, an
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Los aportes de la escuela francesa constituyen
2019-04-19
Los aportes de la escuela francesa constituyen su núcleo central. La formación militar de argentinos por franceses data de 1955. En 1957 el coronel Carlos Rosas, egresado de la Escuela Francesa, asumió la subdirección de la Escuela Superior de Guerra y en 1959 se suscribieron una serie de convenios
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The PAX gene encodes a transcriptional factor which
2019-04-19
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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br Sustained monomorphic ventricular tachycardia br Monomorp
2019-04-19
Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr
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Genomic DNA was isolated from blood after
2019-04-19
Genomic DNA was isolated from blood after obtaining written informed consent. Genetic screening for LQT-1 (KCNQ1), -2 (KCNH2), -3 (SCN5A), -5 (KCNE1), -6 (KCNE2), -7 (KCNJ2), -9 (CAV3), -10 (SCN4B), and -12 (SNTA1) was performed by PCR and direct DNA sequencing. No CEP-37440 was found in these gene
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Introduction Osteosarcoma OS is the most common type
2019-04-19
Introduction Osteosarcoma (OS) is the most common type of bone tumor occurred in adolescents and children [1]. OS is highly malignant and accounts for about half of bone sarcomas with high potential of metastasis [2]. Treatment for OS is mainly depended on surgical operation, assisted with chemothe
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br Discussion Debate persists about
2019-04-19
Discussion Debate persists about how to best define the ER ECG pattern. There is consensus regarding definition of the malignant form of ER as a J-point elevation that could be (or not) associated with ST elevation [1]. In this case, a clear J-point elevation was seen, particularly in lead III (F
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br Conclusion br Conflicts of interest br
2019-04-19
Conclusion Conflicts of interest Clinical case The worldwide estimated prevalence of cardiovascular implantable electronic device (CIED) infection is 1–2%. Prompt removal of infected devices ensures survival [1–4]. We report successful extraction of a lead from an infected CIED by using an
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elastase There is a lot to celebrate and
2019-04-19
There is a lot to celebrate and applaud in this month\'s issue of , but also some sobering findings and a clear demonstration of the need for more research. To start with the positive, Osman Sankoh and fellow INDEPTH Network colleagues announce a new freely accessible repository of Health and Demogr
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Hill and colleagues estimate that globally about
2019-04-19
Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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El otro paradigma cuyo alcance y
2019-04-19
El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso OTX-015 cost la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlemar
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br Case report A year
2019-04-18
Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara
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